NONMEM MCP Server
Supports UIby sueinchoi
Structured access to NONMEM pharmacometric modeling workflows, including parsing and simulation.
What it does
Provides a bridge between AI agents and NONMEM pharmacometric modeling software. It enables the AI to parse model files, analyze results, submit new runs, and perform simulations via mrgsolve.
Tools
read_ext_file: Parse .ext files for parameter estimates and OFV.submit_run: Start NONMEM runs asynchronously.compare_models: Perform multi-run OFV comparison with AIC.translate_to_mrgsolve: Convert NONMEM models to R mrgsolve code.run_diagnostics: Automate checks for boundary, condition number, and shrinkage.
Installation
Add the following to your claude_desktop_config.json:
{
"mcpServers": {
"nonmem": {
"command": "uv",
"args": ["run", "--directory", "/path/to/nonmem-mcp-server", "python", "-m", "nonmem_mcp"],
"env": {
"NONMEM_NMFE_PATH": "/opt/nm760/run/nmfe76"
}
}
}
}
Supported hosts
Confirmed for Claude Desktop and Claude Code.
Quick install
pip install git+https://github.com/sueinchoi/nonmem-mcp-server.gitInformation
- Pricing
- free
- Published
- 7/4/2026
- stars
- 0
Categories
Choose your AI client and follow the steps below.
Claude Desktop
{
"mcpServers": {
"nonmem": {
"command": "uv",
"args": ["run", "--directory", "/path/to/nonmem-mcp-server", "python", "-m", "nonmem_mcp"],
"env": {
"NONMEM_NMFE_PATH": "/opt/nm760/run/nmfe76"
}
}
}
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