UniProt MCP

What it does

Connects LLMs to the UniProt REST API, allowing the AI to retrieve detailed biological data about proteins and proteomics. It transforms the AI into a bioinformatics assistant capable of fetching precise molecular data without manual searching.

Tools

• get_protein_by_accession: Retrieve comprehensive protein details using a UniProt accession number.
• search_proteins: Query the UniProt database for proteins based on keywords, genes, or organisms.
• get_protein_sequences: Fetch amino acid sequences for one or more proteins in FASTA format.
• get_proteomics_data: Access specific protein features including domains, variants, and post-translational modifications.

Installation

Add the following to your claude_desktop_config.json:

{
    "mcpServers": {
        "uniprot": {
            "command": "python",
            "args": [
                "-m",
                "mcp_server",
                "--stdio"
            ]
        }
    }
}

Supported hosts

• Claude Desktop