Precision Oncology Treatment Advisor

What it does

Provides a clinical-focused workflow that interprets tumor molecular profiles and returns prioritized, evidence-graded treatment recommendations. It integrates curated sources (CIViC, OncoKB, ClinVar), checks FDA approval hierarchy, searches trials, and analyzes likely resistance mechanisms to propose next steps.

When to use it

Use in clinical decision-support scenarios where a cancer type and molecular alterations are available and clinicians need prioritized therapy options, resistance explanations, or trial eligibility leads. Not for definitive clinical decisions without human oncologist review.

What's included

• Scripts: none listed in SKILL.md, but extensive cross-references and procedural checklists are provided.
• References: multiple docs and example workflows (TOOLS_REFERENCE, REPORT_TEMPLATE, EXAMPLES, CHECKLIST).
• Instructions: explicit phase-by-phase workflow (profile validation, variant interpretation, treatment options, resistance analysis, trials, literature) and tool parameter guidance.

Compatible agents

Best for medically-oriented agent toolchains with access to biomedical databases and literature tools (specialist research agents, ToolUniverse integrations, Claude/GPT agents with medical tool access). Requires human oversight for clinical use.