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Access the BRENDA enzyme database via SOAP API to retrieve kinetic parameters, reactions, organism data, and substrate-specific enzyme information.
BRENDA (BRaunschweig ENzyme DAtabase) is a comprehensive enzyme information system. This skill provides helpers and scripts to query kinetic parameters (Km, kcat), reaction equations, organism-specific enzyme data, and environmental/condition metadata.
scripts/brenda_queries.py, scripts/brenda_visualization.py, scripts/enzyme_pathway_builder.py).get_km_values("1.1.1.1") (via provided client)search_enzymes_by_substrate("glucose", limit=20)The skill includes detailed parsing and workflow examples. Users must provide valid BRENDA credentials and respect API rate limits.
BRENDA Database Client skill provides extensive documentation for querying enzyme kinetic data via the BRENDA SOAP API. The SKILL.md is comprehensive and well-structured for reference, but the skill references three scripts (brenda_queries.py, brenda_visualization.py, enzyme_pathway_builder.py) and a brenda_client module that are not bundled — only the SKILL.md body was available with no actual script files. The code examples are illustrative Python snippets rather than executable scripts. Authentication requires BRENDA credentials stored in .env, which is appropriate but adds friction.
Skill is documentation-only with no bundled scripts. The referenced Python modules and helper scripts don't ship with the skill, making it more of a reference guide than an executable skill. Security is reasonable (no hardcoded creds, no destructive commands, uses .env for auth), but the SOAP API calls to external BRENDA servers constitute network calls to an external host (-18 deduction considered, though BRENDA is a well-known legitimate scientific database so partial credit). Shell injection risk from the legacy BRENDA_EMIAL typo environment variable handling is minimal. The SKILL.md itself is extensive and well-written as documentation, but lacks executable scripts making it incomplete as a skill. Architecture is mid-range: has proper frontmatter and organized sections but references external scripts not included, and no scripts/ directory with actual code.
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